1. SAIMA PERVAIZ - Assistant Professor, Immunology Department, University of Health Sciences, Lahore.
2. ALIYA ASLAM - Associate Professor, Pathology Department, Azra Naheed Medical College, Lahore.
3. ASMA ARSHAD - Assistant Professor, Biochemistry Department, Continental Medical College, Lahore.
4. AMBREEN TAUSEEF - Professor, Physiology Department, CMH Lahore Medical College & Institute of Dentistry, Lahore.
5. UZMA NASEER - Professor, Department of Anatomy, CMH Lahore Medical College & Institute of Dentistry, Lahore.
6. SIDRA YASIR - Senior Lecturer, Physiology Department, Shalamar Medical & Dental College, Lahore.
Objective: Clomiphene is one of the drugs of choice which is given for the treatment of anovulation. In PCOS anovulation is the main reason for infertility therefore this drug is used along with other medicine therapies. Clomiphene citrate also affects the female gonadal hormones FSH, LH, estrogen and progestron.as level of these hormones is altered in PCOS. This drug controls the hypersecretion of LH. This study was to evaluate the effects of drugs on female gonadal hormones. Ovarian response for ovulation is observed by serum level of these hormones and ultrasound to monitor the follicle size. This research will help clinicians to demonstrate the benefits of clomiphene and its uses to treat infertility in patients with PCOS and other anovulation conditions.
PCOS, Clomiphene citrate, anovulation, progestogen, estrogen, luteinizing hormone, follicle, stimulating hormone.