The amounts of creatinine "in the blood ranged from 3 to 14 mg/dl, with the mean being 7.34 mg/dl. The serum calcium level was found to be low in ten patients, normal in twenty-eight patients, and elevated in twelve individuals. Twelve individuals had low serum phosphorus levels, whereas the other 38 patients had levels that were within normal range. T3 levels were measured between 0.2 and 2.0ng/ml, with the mean being 0.67 (normal range 0.6 – 2.1ng/ml), T4 levels were measured between 0.9 and 8.4g/dl, with the mean being 5.65 (normal range 5-135g/dl), and serum TSH levels were measured between 0.6 and 37 IU/ml, with the mean being 6.49 (normal range 0.4-7 IU/ml). We found that 29 patients had low T3 syndrome, 12 individuals had low T4 syndrome, and four patients had hypothyroidism in our research. The signs of hypothyroidism were seen in 34 individuals who made up the study group. In this paper, the incidence of Low T3 syndrome increased in tandem with the progression of age. We discovered that the frequency of patients with low T3 rises as the severity of chronic renal disease increases, according to our research. Patients with low T4 syndrome have a higher risk of developing kidney failure than those without the condition. The serum T3 level was shown to be reduced in individuals with poor GFR. There is no connection between mean TSH levels in patients with low T3 syndrome and GFR levels in patients with different stages of renal illness in patients with low T3 syndrome. The low T3 condition of chronic kidney disease (CKD) may be considered protective, since it promotes protein conservation.