Learning disabilities (LDs) have become one of the most frequent challenges for teachers, the family, and for the students who have them. It is imperative to note that one of the most common problems experienced by school children is learning disability. Aim; This study aimed to evaluate the effect of nursing intervention program on psychological stress and competences among parents of children with learning disabilities. Study design; a quasi-experimental design was utilized to conduct this study. Setting; this study was conducted at four private centers of learning disabilities at Zagazig city (the most important center in each zone (eastern, western, northern, southern) Namaa center, Ataa center, early intervention & child development center, and tamkeen center. Subject; convenient sample of70 parents of children with L.D were chosen for conducting this study. Data collection tools: 1) Socio-demographic data sheet, 2) parent stress index, 3) parenting sense of competence scale. Results; The results of this study showed there was significant difference in the stress and competence level during post program implementation compared to preprogram implementation. Conclusion; the study concluded that parents of children with L.D had high levels of psychological stress and low level of competences, which improved after implementation of the nursing intervention program with a highly statistical significance difference (p value ≤ 0.01). Recommendation; The current study recommended that, structured psycho- educational program should be developed for parents having children with L.Ds to increase their knowledge about caring and dealing with L.Ds children.