Manuscript Title:

EXPLORING NOVEL THERAPEUTIC APPROACHES FOR ALLERGIC RHINITIS IN CHILDREN: CURRENT TRENDS AND FUTURE PERSPECTIVES

Author:

MUHAMMAD IMRAN ARIF, LIANG RU, YANAN WANG

DOI Number:

DOI:10.17605/OSF.IO/QKH73

Published : 2023-08-10

About the author(s)

1. MUHAMMAD IMRAN ARIF - Resident- MD Pediatrics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang-China.
2. LIANG RU - Associate Professor of Pediatrics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang-China.
3. YANAN WANG - Resident-MD Pediatrics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang-China.

Full Text : PDF

Abstract

Allergic rhinitis is the most common chronic disease affecting children and is frequently undiagnosed and untreated due to their limited ability to express symptoms. This condition significantly impacts psychosocial well-being, learning capacity and quality of life and is associated with potential complications like asthma, sinusitis and otitis media. Recognizing signs such as allergic shiners, creases and salute is vital for identification. Allergic rhinitis arises from an immune overreaction to environmental allergens, triggering the release of inflammatory mediators. Symptoms include congestion, sneezing, itching and rhinorrhea. Treatment options emphasize environmental control, although complete allergen avoidance may not be feasible. Initial therapy comprises nonsedating second-generation oral antihistamines, while intranasal corticosteroids offer effective relief with fewer systemic side effects. Decongestants may be necessary and allergen immunotherapy injections can be considered for persistent cases. Clinicians must consider factors influencing compliance in pediatric patients. Rapid intervention and tailored management are crucial for improving outcomes and minimizing the allergic rhinitis impact in children.


Keywords

Allergen immunotherapy, allergic rhinitis, antihistamines, pediatrics.