Objectives: The purpose of the research article is to differentiate between the efficacy of Positional Release Therapy (PRT) and Myofascial release technique (MRT) in reducing pain and disability among Frozen Shoulder patients. Methodology: An experimental study was conducted with a sample size of 30. Group A (n=15) was given positional release therapy, and group B (n=15) was given myofascial release therapy. Data were collected from Bone Care Trauma Center Hyderabad, Sindh, Pakistan. For the analysis of the data, SPSS (Statistical Package of Social Sciences) version 23 was used. The study makes use of descriptive and inferential statistics to calculate Mean and Paired and independent t-tests. Result: Present study concluded that both the techniques MRT and PRT has were found effective in reducing pain intensity and decreasing functional disability among patients with frozen shoulders. Furthermore, significant improvement was observed in all parameters of active and passive range of motion (ROM) in both the groups except medial rotation (MR) during active ROM in the myofascial release group when analyzed within the groups. No significant difference was found in active and passive flexion, extension, and abduction ROM while a significant difference was found in passive lateral rotation (LR) and active and passive medial rotation (MR). Conclusion: It has been concluded that Myofascial Release Therapy is more effective than Positional Release Therapy in a patient with a frozen shoulder. The study recommends conducting further research to study the intermediate and long-term effects of MRT and PRT on special populations, such as diabetic mellitus, etc.