The leaves and branches of two plants species Citrullus colocynthis and Salvadora oleoides were obtained to acquire powder. The mixed powder was applied individually at 5g and 10g concentration against Rhyzopertha dominica and Trogoderma granarium. Studies were carried out from August-2021 to March- 2022 under controlled laboratory conditions. The observations were made on the concern parameters such as, Mortality rate, Weight loss and Supplement damage of the grain. Results revealed that non-significantly maximum mortality of both pests were recorded 57.0% and 58.0% at 10g dosage of C. colocynthis powder in the month of December-2021. While the minimum mortality 1.0% and 2.0% was observed at 5g dosage of S. oleoides plant powder during August -2021. Maximum weight loss and Insect damage to grain were found on 5g of S. oleoides powder 17.0%, 31.3% and 15.0%, 29.2% to R. dominica and T. granarium. On the contrary low weight loss and insect damage 7.1%, 22.1% and 9.1%, 24.3% were recorded at 5g powder dosage of C. colocynthis. Present findings would be helpful for the effectiveness of these tested plants as grain protectants versus stored grain pests especially in the advancement of pest management strategies.