1. MANOJ KUMAR NANDKEOLIAR - Professor, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital,
Sharda University, Greater Noida, Uttar Pradesh, India.
2. AMBER - MD First Year, Department of Biochemistry, School of Medical Sciences and Research and Sharda
Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
3. THURAYA ABDULLSALAM AA ALAZAZI - PhD Scholar, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
4. BHASKAR CHARANA KABI - Professor, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital,
Sharda University, Greater Noida, Uttar Pradesh, India.
The third greatest cause of mortality worldwide is Chronic Obstructive Pulmonary Disease (COPD), a progressive and long-term illness that obstructs airways. Genetic and environmental variables both have an impact on COPD. COPD patients' lungs and airways have a chronic inflammatory response that is brought on by smoking, biomass smokes, home pollutants, etc. These trigger neutrophils and macrophages resulting in release of various cytokines along which, the proinflammatory cytokine IL1β is the most frequently found innate immune cytokine associated with COPD. In this review we are discussing the variations in the association of serum levels of IL1β in COPD and also in the polymorphism of IL1β in COPD patients.
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) AND ITS ASSOCIATION WITH INTERLEUKIN 1 BETA: AN UPDATE