Manuscript Title:

HIGH-SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) AND SUBCLINICAL HYPOTHYROIDISM (SCH): AN UPDATE

Author:

MANOJ KUMAR NANDKEOLIAR, KASAK CHAUDHARY, THURAYA ABDULLSALAM AA ALAZAZI, NIRUPMA GUPTA, BHASKAR CHARANA KABI

DOI Number:

DOI:10.5281/zenodo.10877591

Published : 2024-03-23

About the author(s)

1. MANOJ KUMAR NANDKEOLIAR - Professor, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
2. KASAK CHAUDHARY - M.Sc. Medical Biochemistry Final year, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
3. THURAYA ABDULLSALAM AA ALAZAZI - PhD Scholar, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
4. NIRUPMA GUPTA - Professor, Department of Anatomy, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
5. BHASKAR CHARANA KABI - Professor, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.

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Abstract

hs-CRP, an acute phase protein and a biomarker of inflammation. It is an indicator of future cardiovascular events. Elevated hs-CRP levels are seen with hypothyroidism. The relation between hs-CRP and SCH, is discussed in the latter part. SCH, defined by elevated thyroid-stimulating hormone levels as per the Indian Thyroid Society Patients diagnosed with SCH, TSH levels is 4.5–10 mIU/L, may progress to overt hypothyroidism. Considering that the condition is subclinical, a significant percentage of the population goes undiagnosed. It is necessary to implement health campaigns to identify these patients at an early stage.


Keywords

HIGH-SENSITIVITY C-REACTIVE PROTEIN (hs-CRP) AND SUBCLINICAL HYPOTHYROIDISM (SCH): AN UPDATE