Manuscript Title:

HYPERTENSION AND INTERLEUKIN 1 BETA, A POSSIBLE BIOMARKER?

Author:

BHASKAR CHARANA KABI, SUNITHA ROSY ANOOJ, THURAYA ABDULLSALAM AA ALAZAZI, MANOJ KUMAR NANDKEOLIAR

DOI Number:

DOI:10.5281/zenodo.10877643

Published : 2024-03-23

About the author(s)

1. BHASKAR CHARANA KABI - Professor, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
2. SUNITHA ROSY ANOOJ - MD Second Year, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
3. THURAYA ABDULLSALAM AA ALAZAZI - PhD Scholar, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
4. MANOJ KUMAR NANDKEOLIAR - Professor, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.

Full Text : PDF

Abstract

Hypertension, or high blood pressure (BP), a chronic, preventable, non-communicable disease regarded numerously as a noteworthy danger sign for cardiovascular diseases (CVD). Evidence have showcased the connecting link between chronic inflammation and hypertension implementing that during body’s phase of chronicity, the immune system of our body triggers cells, such as monocytes, macrophages, neutrophils promoting the secretions of inflammatory cytokines may be interleukin 1 beta (IL-β) causing vascular permeability under the building up and release of Radical Oxygen Species (ROS) which promotes sustained chronic condition of the vascular endothelium. Therefore, we envisage that this review will strengthen the public understanding regarding the pathophysiological mechanisms and correlation of interleukin 1 beta in hypertension.


Keywords

HYPERTENSION AND INTERLEUKIN 1 BETA, A POSSIBLE BIOMARKER?