The Surveillance of surgical site infections (SSI) is a priority in our facility. In the Rhino-Laryngology department, the SSI incidence has significantly decreased since it joined the active surveillance network in 2006. The Aims are Calculate the incidence of surgical site infections and to identify risk factors for infections and Identify the risk factors associated with the occurrence of SSI. It’s a prospective study of surgical site infections (SSI) for analytical purposes. Data collection was carried out from 1st February to the 30th March 2019 with a follow-up up to 30 days. The SSI diagnosis was based on the CDC Atlanta criteria. The analysis of the data was carried out on the EPI-INFO6.04 software. A total of 326 interventions were included. The sex ratio was 0.93, the mean age was 34.9 +/- 18 years. 85.1% had an ASA score = 1, the average length of stay was 4.4 +/- 0.2 days. The percentage of patients reviewed on D30 was 93.5%. Two thirds of the interventions were contaminated clean interventions, and half had an NNIS = 0 score, no emergency intervention was performed, 14 patients contracted an SSI in an average time of 4 +/- 0.4 days, an overall SSI incidence rate of 4.3% (95% CI = [2.1 - 6.5], mean age of infected patients was 44+ /-17.2 years. The incidence rate was 41.7% for the ASA score 2 versus 2.9% for the ASA 1 score, and the incidence of infections was significantly greater when the Altemeier class was contaminated (8.5% versus 2.6%, p 1 (p<0.001). In Conclusion, The monitoring of SSI in ORL has highlighted risk factors that should be taken into account in order to improve the management and prevention of risks related to surgical care. However, the improvement of preventive measures must be pursued by influencing extrinsic risk factors. (Justify, Calibri 8)