Manuscript Title:

HYPERURICEMIA: EMERGING COMORBIDITY OR SIMPLE PRECURSOR?

Author:

BILAL BENGANA, SALIMA LEFKIR TAFIANI

DOI Number:

DOI:10.5281/zenodo.11031804

Published : 2024-04-23

About the author(s)

1. BILAL BENGANA - Rheumatologist, Rheumatology Department, Beni Messous University Hospital, Algiers, Algeria.
2. SALIMA LEFKIR TAFIANI - Chief, Rheumatology Department, Beni Messous University Hospital, Algiers, Algeria.

Full Text : PDF

Abstract

Hyperuricemia, characterized by elevated levels of uric acid in the blood, has garnered significant interest due to its increasing prevalence globally. This condition is often associated with dietary changes, such as increased consumption of sugary and alcoholic beverages, as well as a diet rich in purines. The consequences of hyperuricemia extend beyond gout, with established links to other pathologies such as metabolic syndrome, type 2 diabetes, hypertension, and renal insufficiency. This correlation raises the pivotal question of whether asymptomatic hyperuricemia should be treated. Managing hyperuricemia and its consequences involves hygienic and dietary approaches as well as specific treatments to lower uric acid levels in the blood. Advances in understanding the pathophysiology of gout and uric acid metabolism have led to the development of new therapeutic options. However, uncertainties persist regarding the optimal management of asymptomatic hyperuricemia, necessitating further research to determine relevant risk factors and the ideal timing to initiate urate-lowering therapy. This review explores the various aspects of hyperuricemia, from its clinical implications to its management strategies, providing a comprehensive overview of this increasingly concerning condition in the realm of health.


Keywords

Gout, Hyperuricemia, Consequence.