Manuscript Title:

UNCOMMON MALIGNANT BREAST CONDITIONS MIMICKING BENIGN FINDINGS: CASE STUDIES AND REVIEW OF THE LITERATURE

Author:

RADIA BENYAHIA, CHAHIRA MAZOUZI, KAMEL HAIL, NABIL BELLIK, NAZIM LARABA

DOI Number:

DOI:10.5281/zenodo.11056304

Published : 2024-04-23

About the author(s)

1. RADIA BENYAHIA - Medical Imaging Department, Pierre and Marie Curie Center, University of Algiers 1, Algeria.
2. CHAHIRA MAZOUZI - University Hospital of Bejaia, Medical Oncology Department, University of Bejaia.
3. KAMEL HAIL - University Hospital of Mustapha, Surgery Department, University of Algiers 1.
4. NABIL BELLIK - University Hospital of Bejaia, Nephrology Department, University of Bejaia.
5. NAZIM LARABA - University Hospital of Bab El Oued, Internal Medicine Department, University of Algiers 1.

Full Text : PDF

Abstract

Deceptive cancers mimic benign breast tumors and are primarily represented by the group of round-shaped cancers with well-circumscribed contours. These account for about 10 to 20% of breast cancers. They most often correspond to grade III invasive carcinomas without specific features, particularly triple-negative cancers. Other etiologies of round-shaped carcinomas correspond to specific histological types including colloid (or mucinous) carcinoma, and medullary carcinoma (especially frequent in patients mutated for BRCA1). It is crucial to recognize their presentation in conventional imaging, mammography, and ultrasound, and to consider them in the presence of morphological criteria of benign appearance (cystic component in ultrasound) combined with subtle non-typical benignity criteria such as the presence of microcalcifications in mammography, microlobulated contours, a complex cystic component in ultrasound, or intratumoral vascularization in Doppler mode. In case of doubt, it is imperative to indicate a micro-biopsy for histological analysis.


Keywords

Breast Cancers, Triple-Negative, Colloid Carcinoma, Medullary Carcinoma, BI-RADS, Mammography, Ultrasound, MRI, Benign Imaging.