Fatty liver disease (FLD) is a growing public health concern often linked to metabolic disorders and lifestyle factors. Self-management strategies had been of great help for both management and preventive purposes. Thus, this study assessed the self-management strategies of FLD among diagnosed patients in selected teaching hospitals in Ogun State, Nigeria. A cross sectional descriptive design was utilized for the study using the total enumeration of 244 diagnosed patients. A structured and validated 23 items questionnaire was used, and data collection spanned for four (4) weeks using descriptive analysis. The findings showed that the knowledge level is moderate, perceived severity of fatty liver disease is high, self-management strategies was moderate, and the perceived barriers to the adoption of self-management strategies was high. The study concluded that knowledge, and severity of the disease condition. It is recommended that patient education and awareness be enhanced to foster better understanding and adherence to treatment.