BACKGROUND: Biliary tract cancers, which include tumors of the gallbladder, extra hepatic bile duct, and ampulla of Vater, are uncommon but deadly diseases. Tobacco and alcohol are well-known risk factors for a variety of cancers, and the International Agency for Research on Cancer has classified them as group 1 carcinogens. Tobacco use is the leading cause of cancer in the world. Despite a large body of research on tobacco and alcohol, the link between these exposures and biliary tract cancers remains unknown. METHODOLOGY: Respondents were interviewed in-person by trained interviewers using a structured questionnaire to obtain information on demographic characteristics, lifestyle behaviors, and medical histories. Based on the responses of the respondents the sample size was 66 from Coimbatore city. SPSS version 17 was used to carry on the statistical analysis for the study. RESULT: In the current study it was identified that among the selected respondents majority were from age group of above 56 years, 60.61 percent were female respondents and were married 43.94 percent were from middle income family and have attained middle education and 65.15 percent were from rural area. 56.06 percent did not have any comorbidities and they were not alcohol consumers and were not smokers and the majority of them were non vegetarians. There was relationship between general characteristics and Co morbidity and there was an association between comorbidity, consanguinity, stage of tumor and size of tumor.