This review provides an in-depth exploration of the crucial role that school nurses play in promoting mental health and well-being among students. As frontline health professionals within the educational setting, school nurses are often the first to identify and address mental health issues among students, making their role pivotal in the early detection, intervention, and management of these concerns. This review delves into the various aspects of their role, including health promotion, disease prevention, health education, and the provision of direct healthcare services. It also examines the challenges faced by school nurses in fulfilling this role and discusses potential solutions and opportunities for improvement. Through a blend of research, case studies, and practical examples, the review underscores the importance of school nurses as integral members of the school community and their significant contribution to fostering a healthy, safe, and supportive learning environment conducive to the mental well-being of students