Background: Diabetes in children is becoming an increasingly important public health concern throughout the world. It is associated with many serious complications. Self-management is essential to prevent or delay such complication. Aim: was to evaluate the effect of a stepwise program on preventing diabetic complications among children suffering from diabetes mellitus. Design A Quasi experimental design pre and post-test was utilized achieve aim of this study. Setting conducted at pediatric in patient and out-patient unit in Beni-Suef university hospital. Sample a convenience sample composed of 60 children and their accompanying mothers. Tools: three tools was used; first tool structured questionnaire and child assessment sheet, second tool diabetes self-management questionnaire, and third tool was observational checklists for diabetic self-care practices. Results: Significant improvement in the mean total scores of diabetic self-care management in post-program (38.73±5.85) compared to pre-program (17.80±8.86). At post program, there were significant improvements in all procedures after stepwise program. Conclusion: Stepwise program was prevent diabetic complications among children suffering from diabetes mellitus observed by increased mean total scores of diabetic self-care management and practices post-program. Recommendations: Health care providers should promote diabetes self- care programs for children with diabetes mellitus to enhance diabetic's self- care practices and prevent diabetes related complications.