Manuscript Title:

OLFACTORY FUNCTION COMPARASION IN COVID-19 PATIENTS BEFORE AND AFTER NASAL WASHING WITH ISOTONIC AND HYPERTONIC SOLUTIONS

Author:

PERKASA MUH. FAJAR, MOKOAGOW SUBARI, AZIS AMINUDDIN, ABDUL QADAR PUNAGI, RAHARDJO SUTJI PRATIWI, SEWENG ARIFIN

DOI Number:

DOI:10.17605/OSF.IO/5RWNE

Published : 2022-05-10

About the author(s)

1. PERKASA MUH. FAJAR - Otorhinolaryngology Head and Neck Surgery Department, Faculty of Medicine Hasanuddin University, Wahidin Sudirohusodo Hosipital, Makassar, Indonesia.
2. MOKOAGOW SUBARI - Otorhinolaryngology Head and Neck Surgery Department, Faculty of Medicine Hasanuddin University, Wahidin Sudirohusodo Hosipital, Makassar, Indonesia.
3. AZIS AMINUDDIN - Otorhinolaryngology Head and Neck Surgery Department, Faculty of Medicine Hasanuddin University, Wahidin Sudirohusodo Hosipital, Makassar, Indonesia.
4. ABDUL QADAR PUNAGI - Otorhinolaryngology Head and Neck Surgery Department, Faculty of Medicine Hasanuddin University, Wahidin Sudirohusodo Hosipital, Makassar, Indonesia.
5. RAHARDJO SUTJI PRATIWI - Otorhinolaryngology Head and Neck Surgery Department, Faculty of Medicine Hasanuddin University, Wahidin Sudirohusodo Hosipital, Makassar, Indonesia.
6. SEWENG ARIFIN - Biostatistics and Epidemiology Department, Faculty of Public Health Hasanuddin University, Makassar, Indonesia.

Full Text : PDF

Abstract

OBJECTIVE: To compare the olfactory function using the TDI criteria (Olfactory Threshold, Discrimination and Identification olfactory) sniffing stick test in COVID-19 patient’s pre and post using isotonic saline solution and hypertonic solution nasal wash.

METHODS: All patients with positive results of RT-PCR for COVID 19 who experienced olfactory disorders were examined for a sniffing stick test with TDI criteria (Threshold, Identification and Discrimination), samples were given nasal washing with isotonic saline solution and some samples were hypertonic saline, smell function was evaluated again on 7th day and 14th day after giving of nasal wash.

RESULTS: A total of 50 samples with COVID-19 who experienced olfactory function problems, 25 samples were given isotonic saline nasal washing and 25 samples were given hypertonic solutions. The improvement in olfactory function on the 7th day after giving nasal wash in the hypertonic solution group was better when compared to the isotonic saline solution group, while on the 14th day after giving of nasal wash, both isotonic saline and hypertonic solution were not significantly different in the two groups.

CONCLUSION: Olfactory function impairment is one of the early symptoms of COVID-19, nasal washing with isotonic saline solution and hypertonic solution can be suggested as an additional therapy in COVID-19 patients with olfactory disorders.


Keywords

Corona Virus, COVID-19, Anosmia, Hyposmia, Sniffing stick test.