This research was designed to examine the relationship amongst the daily/personal stressors (D/PS) coping and general health (GH) of women working (WW) in different organizations. The purpose was to explore the interactional effect of D/PS and coping strategies (CS) used by women, on their GH. Quantitative survey research design was castoff for data collection. A sample of (N= 300) women was selected from diverse organizations (banks, hospitals & telecom companies) of Lahore city. Participants age was 22 to 50 years, (M=35.55, SD=10.27). Working Women’s Stressors Scale (WWSS) Asad & Najam, 2013) was administered to assess stressors; Cope (Carver et al., 1989) was applied to identify CS and general health questionnaire (GHQ 28) (Goldberg & Hillier, 1979) to explore GH. It is concluded that notable positive links existed between D/PS, problem-focused coping (PFC) and GH of WW. Demographic variables, such as the number of dependents, age, job status, and PFC and D/PS are interpreters of GH condition of professional women. Results also suggested that women’s D/PS and PFC have significant interactive effect on their GH. From above findings it was concluded that higher increased D/PS and PFC contributed to health status of WW in banks, hospitals and telecom companies.