Medical nutrition and physical activity management in diabetic patients must be done individually since they must take into account eating habits, metabolism, physical activity, and the existence of comorbidities. Lifestyle adjustments in Type 2 DM patients, such as regulating food adherence and physical exercise, are required to prevent future problems from the disease. Based on this, the purpose of this study is to examine the impact of lifestyle changes on fasting blood glucose levels in Type 2 DM patients. This sort of quasiexperimental research uses a covariance design with dietary prescription interventions and physical activity in the treatment group and nothing (business as usual) in the control group. A fasting blood glucose examination was performed before to receiving a diet prescription intervention and physical exercise in the form of yoga, as well as a fasting blood glucose check after 1 month of intervention, to regulate blood sugar and diet adherence. Purposive sampling was used to choose the research sample, which was accompanied with inclusion and exclusion criteria. This study included 33 samples, with data analysed using ANCOVA. The study found substantial variations in the parameters of BMI (Body Mass Index), fasting blood glucose, and systole before and after the intervention.