Basic tendencies in the emergency surgical measures in case of acute diseases of the abdominal cavity organs within 2019-2021 are discussed in the study. The purpose of the study is establishment of main risk factors of pre-hospital mortality development due to complications of acute surgical diseases of the abdominal organs (ASDAO), effectiveness of primary prevention improvement, its diagnosis and management using innovative technologies. Methods of the study. A comparative analysis of the indicators covering 4 city health care centers where more than 90% of emergency surgeries are performed in case of acute diseases of the abdominal cavity organs of adult population in case of some disease entities combined by the general concept “acute abdomen”. Main risk factors of acute surgical pathologies of the abdominal cavity organs development are low responsibility of people for preservation of their health, nonobservance of dietary pattern, eating of badly digestible food, alcoholic beverages, hypodynamia, absence of regular medical check-up of the patients with chronic pathologies of digestive tract, planned hospital admission and surgical treatment of the patients with ASDAO. The use of audio and video technologies during the medical examination of the abdominal patients has increased for 2019-2022 from 65.43% to 81.31%, a number of patients subject to qualitative planned screening examinations has increased by15.21%, timeliness of medical-preventive activities has been increased by 11.16%, level of planned laboratory-instrumental examination techniques has been grown by 17.72% resulting in increase of share of the patients (11.16%) who were surgically treated on time. Improvement of quality of the periodic health examination of the patients with chronic pathologies of the abdominal cavity organs promoted reduction in the burden of acute appendicitis by 1.19%0, acute pancreatitis by 0.79%0, acute cholecystitis by 0.67%0, gastroduodenal ulcer by 0.48%.