1. BHASKAR CHARANA KABI - Professor, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital,
Sharda University, Greater Noida, Uttar Pradesh, India.
2. AMALESH YADAV - M.Sc, Medical Biochemistry Final Year, Department of Biochemistry, School of Medical Sciences and
Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
3. THURAYA ABDULLSALAM AA ALAZAZI - PhD Scholar, Department of Biochemistry, Department of Anatomy, School of Medical Sciences and Research and Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
4. NIRUPMA GUPTA - Professor , Department of Anatomy, School of Medical Sciences and Research and Sharda Hospital,
Sharda University, Greater Noida, Uttar Pradesh, India.
5. MANOJ KUMAR NANDKEOLIAR - Professor, Department of Biochemistry, School of Medical Sciences and Research and Sharda Hospital,
Sharda University, Greater Noida, Uttar Pradesh, India.
The most common thyroid disorder among Indian population is Subclinical Hypothyroidism (SCH). Inflammatory markers can assist to identify consequences of Subclinical Hypothyroidism. In this review we discuss the impact of interleukin-6, an inflammatory marker, on individuals with SCH. In Subclinical Hypothyroidism, TSH levels are slightly higher (4.5-10 mIU/L) but Triiodothyronine (T3) and Thyroxine (T4) levels remain normal, indicating that increased TSH is related with increased interleukin-6. Evaluating the factors that may decrease the risk of prognosis of patients with SCH to overt hypothyroidism is needful. Further studies required to identify the risk factors including inflammatory markers like IL-6 and other cytokines and their effect on SCH.
SUBCLINICAL HYPOTHYROIDISM AND INTERLEUKIN 6 (IL-6): - A SHORT REVIEW